BDBM50082665 4-(dimethylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)benzamide::4-Dimethylamino-N-(6-hydroxycarbamoyl-hexyl)-benzamide::CHEMBL140000::US10188756, Compound CN52

SMILES CN(C)c1ccc(cc1)C(=O)NCCCCCCC(=O)NO

InChI Key InChIKey=MXWDSZWTBOCWBK-UHFFFAOYSA-N

Data  17 IC50

PDB links: 17 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50082665   

TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Freiburg

Curated by ChEMBL
LigandPNGBDBM50082665(4-(dimethylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)...)
Affinity DataIC50:  2.96E+3nMAssay Description:Inhibition of FLAG-tagged HDAC1 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Rattus norvegicus)
University Of Freiburg

Curated by ChEMBL
LigandPNGBDBM50082665(4-(dimethylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)...)
Affinity DataIC50:  240nMAssay Description:Inhibition of HDAC1 in rat liver extractMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Freiburg

Curated by ChEMBL
LigandPNGBDBM50082665(4-(dimethylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)...)
Affinity DataIC50:  7.30nMAssay Description:All histone deacetylases were purchased from BPS Bioscience. The substrates, Broad Substrate A, and Broad Substrate B, were synthesized and are now a...More data for this Ligand-Target Pair
In DepthDetails US Patent